bs-4592R-Biotin [Conjugated Primary Antibody]
CDKN2A/p16INK4a Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CDKN2A/p16INK4a

Specificity: Targets p16INK4a

Immunogen Range: 31-100/156


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1029

Swiss Prot: P42771

Source: KLH conjugated synthetic peptide derived from human CDKN2A

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 15


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhao, Yi, et al. "Pokemon enhances proliferation, cell cycle progression and anti-apoptosis activity of colorectal cancer independently of p14ARF–MDM2–p53 pathway." Medical Oncology 31.12 (2014): 1-8.Read more>>
  • Xuan Zheng. et al. Ultraviolet B irradiation up\regulates MM1 and induces photoageing of the epidermis. 2021 Feb 23Read more>>