bs-4529R-BF350 [Conjugated Primary Antibody]
NDV HN protein Polyclonal Antibody, AbBy Fluor® 350 Conjugated
www.biossusa.com
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Host: Rabbit

Target Protein: NDV HN protein

Clonality: Polyclonal

Isotype: IgG

Swiss Prot: P32884

Source: recombinant protein corresponding to amino acids 49 to 577 out of the full length (577 amino acids) Newcastle disease virus Hemagglutinin-neuraminidase protein

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV) plays a crucial role in the process of infection. It attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion.

Conjugation: AbBy Fluor® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:500-1000)

Predicted Molecular Weight: 63


Cross Reactive Species: Virus
Others
(Newcastle disease)

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wei, Ding, et al. "Oncolytic Newcastle disease virus expressing chimeric antibody enhanced anti-tumor efficacy in orthotopic hepatoma-bearing mice."Journal of Experimental & Clinical Cancer Research 34.1 (2015): 1.Read more>>
  • o-Kyoung Jung. et al. The human ACE-2 receptor binding domain of SARS-CoV-2 express on the viral surface of the Newcastle disease virus as a non-replicating viral vector vaccine candidate. Plos One. 2022 Feb;17(2):e0263684Read more>>
  • Jiahui Wang. et al. Newcastle disease virus LaSota strain induces apoptosis and activates the TNF/NF-B pathway in canine mammary carcinoma cells. VET COMP ONCOL. 2023 JuRead more>>