bs-4509R [Primary Antibody]
CXCL13/BCA1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CXCL13/BCA1

Immunogen Range: 23-109/109


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 55985

Swiss Prot: O55038

Source: KLH conjugated synthetic peptide derived from mouse CXCL13/BCA1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 10


Cross Reactive Species: Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wang, Lifang, et al. "Chemokine CXCL13 expression was up-regulated in Clostridium difficile infection." Cytokine 88 (2016): 232-240.Read more>>
  • Doloff, Joshua C., et al. "Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates." Nature Materials (2017).Read more>>
  • Expression of Pref-1 and Related Chemokines during theDevelopment of Rat Mesenteric Lymph Nodes.(2018)Biomed Environ Sci.ul;31(7):507-514. Read more>>
  • Tianrui Zhang. et al. Daphnetin Improves Neuropathic Pain by Inhibiting the Expression of Chemokines and Inflammatory Factors in the Spinal Cord and Interfering with Glial Cell Polarization. PHARMACEUTICALS-BASE. 2023 Feb;16(2):243Read more>>
  • Pei-Zhen Han. et al. Distinct tumor microenvironment makes anaplastic thyroid cancer more lethal but immunotherapy-sensitive than papillary thyroid cancer. JCI INSIGHT. 2024 Mar;():173712Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rat liver tissue labeled with Anti-CXCL13 Polyclonal Antibody, Unconjugated (bs-4509R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Lane 1: Human Jurkat cell lysates probed with CXCL13 Polyclonal Antibody, Unconjugated (bs-2553R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.