Host: Rabbit
Target Protein: IREB2
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 3658
Swiss Prot: P48200
Source: KLH conjugated synthetic peptide derived from human IREB2
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C for 12 months.
Background:
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Subcellular Location : Cytoplasm.
Conjugation: Biotin
Excitation/ Emission: N/A
Size: 100ul
Concentration: 1mg/ml
Applications: IHC-P(1:100-500)
Predicted Molecular Weight: 105
Cross Reactive Species:
Human
Mouse
For research use only. Not intended for diagnostic or therapeutic use.