bs-43043P
[Protein]
Recombinant human IL-7Ra protein, C-His (HEK293)
DATASHEET
Entrez Gene: 3575
Swiss Prot: P16871
Source: Recombinant human IL-7Ra protein, C-His (HEK293) protein is expressed in HEK293 with C-His. It contains the amino acid sequence of 21-239/459.
Storage Buffer: 0.01M TBS(pH7.4)
Storage: The product should be stored at -70°C or -20°C.
Background:
The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
Size: 100ug,500ug
Applications: ELISA()
Mol. Wt.: 29.3
Species: Others
For research use only. Not intended for diagnostic or therapeutic use.