bs-43015P-Biotin

DATASHEET

Swiss Prot: P08887

Source: Recombinant human IL-6R alpha protein, Biotin conjugated, C-His protein is expressed in HEK293 with C-His. It contains the amino acid sequence of 1-468/468.

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq].

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ug,500ug

Applications: ELISA()

Mol. Wt.: 42

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.