DATASHEET
Host:
Rabbit
Target Protein:
GLUT8
Immunogen Range:
401-477/477
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
29988
Swiss Prot:
Q9NY64
Source:
KLH conjugated synthetic peptide derived from human GLUT8
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity).
PRODUCT SPECIFIC PUBLICATIONS
- Maria Z, Campolo AR, Lacombe VA (2015) Diabetes Alters the Expression and Translocation of the Insulin-Sensitive Glucose Transporters 4 and 8 in the Atria. PLoS ONE 10(12): e0146033.Read more>>
- Murakami, Ryuta, et al. "Immunoreactivity of glucose transporter 8 is localized in the epithelial cells of the choroid plexus and in ependymal cells." Histochemistry and Cell Biology (2016):1-6.Read more>>
- Gao, Sujie, et al. "Propofol inhibits growth of neurons through regulating insulin receptor and insulin-like growth factor-1 receptor." Int J Clin Exp Pathol 9.7 (2016): 6785-6794.Read more>>
- Mashima, Masato, et al. "Glucose transporter 8 immunoreactivity in astrocytic and microglial cells in subependymal areas of human brains." Neuroscience Letters (2016).Read more>>
- Yoichi Chiba. et al. Glucose, Fructose, and Urate Transporters in the Choroid Plexus Epithelium. Int J Mol Sci. 2020 Jan;21(19):723Read more>>
- Pawe? Jan Stanirowski. et al. Placental expression of glucose transporters GLUT-1, GLUT-3, GLUT-8 and GLUT-12 in pregnancies complicated by gestational and type 1 diabetes mellitus.. 2021 Sep 23Read more>>
- Lin, Guan-Yu. et al. Altered glucose metabolism and its association with carbonic anhydrase 8 in Machado-Joseph Disease. METAB BRAIN DIS. 2022 Apr;:1-18Read more>>
- Changxin Tian. et al. The expression of nutrient chemosensing gate molecules in the ileum and colon is altered for goats fed on a high-grain diet. ANIM SCI J. 2022 Jan;93(1):e13754Read more>>
- Lei Shi. et al. Proteomic analysis reveals the potential positive effects of Mito-TEMPO on ram sperm motility and fertility during cryopreservation. THERIOGENOLOGY. 2023 Jul;205:27Read more>>
- Allison Campolo. et al. Diabetes Causes Significant Alterations in Pulmonary Glucose Transporter Expression. METABOLITES. 2024 May;14(5):267Read more>>
VALIDATION IMAGES
Lane 1: mouse embryo lysates Lane 2: mouse brain lysates probed with Anti AVPR2 Polyclonal Antibody, Unconjugated (bs-4241R) at 1:200 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in RT. Predicted band 52kD. Observed band size: 52kD.
Lane 1: Mouse Cerebrum tissue lysates; Lane 2: Rat Cerebrum tissue lysates probed with GLUT8 Polyclonal Antibody, Unconjugated (bs-4241R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.