bs-4239R-Cy7 [Conjugated Primary Antibody]
BNIP3 Polyclonal Antibody, Cy7 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: BNIP3

Immunogen Range: 101-194/194


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 664

Source: KLH conjugated synthetic peptide derived from human BNIP3

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.

Conjugation: Cy7

Excitation/ Emission: 743nm/767nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)

Predicted Molecular Weight: 22


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Cow
Pig
Horse
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Du et al. MicroRNA-145 induces apoptosis of glioma cells by targeting BNIP3 and Notch signaling. (2017) Oncotarget. 8:61510-61527Read more>>
  • Ruiqiao Guan. et al. Electroacupuncture at GV20?GB7 regulates mitophagy to protect against neurological deficits following intracerebral hemorrhage via inhibition of apoptosis. Mol Med Rep. 2021 Jul;24(1):1-15Read more>>
  • Kaidi Ma. et al. Lactobacillus rhamnosus GG ameliorates deoxynivalenol-induced kidney oxidative damage and mitochondrial injury in weaned piglets. Food Funct. 2022 MaRead more>>
  • Qifeng Deng. et al. Cordycepin enhances anti-tumor immunity in colon cancer by inhibiting phagocytosis immune checkpoint CD47 expression. Int Immunopharmacol. 2022 Jun;107:108695Read more>>
  • He Bai. et al. Inhibition of the BNIP3/NIX-dependent mitophagy aggravates copper-induced mitochondrial dysfunction in duck renal tubular epithelial cells. ENVIRON TOXICOL. 2022 NovRead more>>
  • Qian Zhang. et al. Expression of HIF1, BNIP3, and beclin-1 in the brain of newborn and adult yaks (Bos grunniens). FOLIA HISTOCHEM CYTO. 2023 Mar;61(1):26-33Read more>>
  • Changbin Zhao. et al. IGF2 promotes the differentiation of chicken embryonic myoblast by regulating mitochondrial remodeling. J CELL PHYSIOL. 2024 JuRead more>>
  • Jia-Jun Wu. et al. Heyingwuzi formulation alleviates diabetic retinopathy by promoting mitophagy via the HIF-1/BNIP3/NIX axis. WORLD J DIABETES. 2024 Jun 15; 15(6): 13171339Read more>>
  • Jinfeng Shang. et al. Naoxintong capsule accelerates mitophagy in cerebral ischemia-reperfusion injury via TP53/PINK1/PRKN pathway based on network pharmacology analysis and experimental validation. J ETHNOPHARMACOL. 2024 Aug;:118721Read more>>