Host: Rabbit
Target Protein: IL-18
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 29197
Swiss Prot: P97636
Source: Recombinant rat IL-18 protein
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C for 12 months.
Background:
IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Conjugation: Biotin
Excitation/ Emission: N/A
Size: 100ul
Concentration: 1mg/ml
Applications:
ELISA(1:5000-10000)
IHC-P(1:100-500)
Predicted Molecular Weight: 22
Cross Reactive Species: Rat
Predicted Cross Reactive Species: Mouse
For research use only. Not intended for diagnostic or therapeutic use.
- Kaixin Wang. et al. Long-Term Alcohol Exposure Aggravates Ischemic Stroke-Induced Damage by Promoting Pericyte NLRP3 Inflammasome Activation via Pre-Activating the TLR4/NF-B Pathway in Rats. J INFLAMM RES. 2024 23Read more>>