DATASHEET
Host:
Rabbit
Target Protein:
DMBT1
Immunogen Range:
215-420/2085
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
1755
Swiss Prot:
Q9UGM3
Source:
Recombinant mouse DMBT1 protein
Purification:
Purified by Protein A.
Storage Buffer:
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
DMBT 1 may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular(oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophages tissues throughout the body, including epithelial cells lining the gastrointestinal tract. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. [Subcellular Location] Secreted. Membrane. [Tissue Specificity] Expressed in von Ebner glands (VEG) (at protein level), olfactory epithelium and the lateral nasal gland. Expressed in transit-amplifying ductular (oval) cells. Up-regulated at day 3 after hepatectomy. Expressed in newly formed bile ducts and in structures resembling intestinal epithelium. Belongs to the DMBT1 family.
Conjugation:
AbBy Fluor® 750
Excitation/ Emission:
749nm/775nm
Size:
100ul
Concentration:
1ug/ul
Applications:
WB(1:300-5000)
227
Mouse
Predicted Cross Reactive Species:
Rat
For research use only. Not intended for diagnostic or therapeutic use.