DATASHEET
Swiss Prot:
P37840
Source:
Recombinant human Alpha-synuclein protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 1-140/140.
Storage Buffer:
0.01M TBS(pH7.4)
Storage:
The product should be stored at -70°C or -20°C.
Background:
Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].