bs-4177R-Biotin [Conjugated Primary Antibody]
SOX9 Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: SOX9

Immunogen Range: 121-220/509


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6662

Swiss Prot: P48436

Source: KLH conjugated synthetic peptide derived from human SOX9

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 56


Cross Reactive Species: Human
Mouse
Rat
Rabbit

Predicted Cross Reactive Species: Dog
Cow
Pig
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wang, Wei, et al. "Overexpression of heparan sulfate 6-O-sulfotransferase-2 enhances fibroblast growth factor-mediated chondrocyte growth and differentiation." International Journal of Molecular Medicine 36.3 (2015): 825-832.Read more>>
  • Montorsi, Lucia, et al. "Loss of zfp36 expression in colorectal cancer correlates to wnt/ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of zeb1, sox9 and macc1." Oncotarget (2016).Read more>>
  • Webster, Mark K., et al. "Evidence of BrdU Positive Retinal Neurons after Application of an Alpha7 Nicotinic Acetylcholine." Neuroscience (2017).Read more>>
  • Mi, Jie, et al. "Study of the effect of miR‑124 and the SOX9 target gene in Hirschsprung's disease." Molecular medicine reports 9.5 (2014): 1839-1843.Read more>>
  • Yang, Jinjiang, Ying Lu, and Ai Guo. "Platelet-rich plasma protects rat chondrocytes from interleukin-1β-induced apoptosis." Molecular Medicine Reports 14.5 (2016): 4075-4082.Read more>>
  • Chang et al. The repair of full-thickness articular cartilage defect using intra-articular administration of N-acetyl-D-glucosamine in the rabbit knee: randomized controlled trial. (2015) Biomed.Eng.Onlin. 14:105Read more>>
  • Wu et al. Subchondral bone changes and chondrogenic capacity of progenitor cells from subchondral bone in the collagenase-induced temporomandibular joints osteoarthritis rabbit model. (2015) Int.J.Clin.Exp.Patho. 8:9782-9Read more>>
  • Papaioannou et al. MicroRNA-140 Provides Robustness to the Regulation of Hypertrophic Chondrocyte Differentiation by the PTHrP-HDAC4 Pathway. (2015) J.Bone.Miner.Res. 30:1044-52Read more>>
  • Chen XY et al. Pulsed Magnetic Field Stimuli Can Promote Chondrogenic Differentiation of Superparamagnetic Iron Oxide Nanoparticles-Labeled Mesenchymal Stem Cells in Rats.(2018) J Biomed Nanotechnol. 14(12):2135-2145. Read more>>
  • "Zhuang M et al. Reelin regulates male mouse reproductive capacity via the sertoli cells.(2018) J. Cell. Biochem. 2018 Oct 18 "Read more>>
  • Fang DP et al. Platelet‐rich plasma promotes the regeneration of cartilage engineered by mesenchymal stem cells and collagen hydrogel via the TGF‐β/SMAD signaling pathway. J Cell Physiol. 2019;1–11.Read more>>
  • Lu H et al. Comparative evaluation of book‐type acellular bone scaffold and fibrocartilage scaffold for bone‐tendon healing. J Orthop Res. 2019 Apr 12. Read more>>
  • Wang HC et al. Intra-articular injection of N-acetylglucosamine and hyaluronic acid combined with PLGA scaffolds for osteochondral repair in rabbits. PLoS One. 2018 Dec 31;13(12):e0209747. Read more>>
  • Tang Y et al. Structure and ingredient-based biomimetic scaffolds combining with autologous bone marrow-derived mesenchymal stem cell sheets for bone-tendon healing. Biomaterials. 2020 May;241:119837.Read more>>
  • Tang Y et al. Structure and ingredient-based biomimetic scaffolds combining with autologous bone marrow-derived mesenchymal stem cell sheets for bone-tendon healing. Biomaterials. 2020 May;241:119837.Read more>>
  • Luo Liwen. et al. Cartilage Endplate Stem Cells Transdifferentiate Into Nucleus Pulposus Cells via Autocrine Exosomes. Front Cell Dev Biol. 2021 Mar;9:482Read more>>
  • Li Taotao. et al. Unraveling Stage-Dependent Expression Patterns of Circular RNAs and Their Related ceRNA Modulation in Ovine Postnatal Testis Development. Front Cell Dev Biol. 2021 Mar;9:65Read more>>
  • Xuejun Dai. et al. Comparison of the differentiation abilities of bone marrow?derived mesenchymal stem cells and adipose?derived mesenchymal stem cells toward nucleus pulposus?like cells in three?dimensional culture. Exp Ther Med. 2021 Sep;22(3):1-9Read more>>
  • Jinjiang Yang. et al. Platelet-rich plasma attenuates interleukin-1-induced apoptosis and inflammation in chondrocytes through targeting hypoxia-inducible factor-2. Tissue Cell. 2021 Sep;:101646Read more>>
  • Sun Tianyu. et al. The Human Positive Cofactor 4 is a Promising Chemotherapeutic Target in Lung Adenocarcinoma. J Oncol. 2021;2021:9958483Read more>>
  • Cheng, Baixiang. et al. Distinctive Roles of Wnt Signaling in Chondrogenic Differentiation of BMSCs under Coupling of Pressure and Platelet-Rich Fibrin. Tissue Engineering and Regenerative Medicine. 2022 Apr;:1-15Read more>>
  • Junchao Huang. et al. Palovarotene inhibits the NF-_B signaling pathway to prevent heterotopic ossification. CLIN EXP PHARMACOL P. 2022 May 31Read more>>
  • Dong Mao. et al. Galunisertib attenuates progression of trauma-induced heterotopic ossification via blockage of Smad2/3 signaling in mice. EUR J PHARMACOL. 2022 Aug;928:175109Read more>>
  • Yan, Wei. et al. Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats. BMC VET RES. 2022 Dec;18(1):1-18Read more>>
  • Huan He. et al. BDE-209 disturbed proliferation and differentiation of spermatogonia during mitotic process through estrogen receptor . REPROD BIOL. 2023 Jun;23:100737Read more>>
  • Jie Su. et al. Study of spermatogenic and Sertoli cells in the Hu sheep testes at different developmental stages. FASEB J. 2023 Jul;37(8):e23084Read more>>
  • Shusei Mizushima. et al. Research Note: Diethylstilbestrol reduces primordial germ cells in male Japanese quail. POULTRY SCIENCE. 2023 Jul;:10291Read more>>
  • Yunxiang Li. et al. Eif2s3y alleviated LPS-induced damage to mouse testis and maintained spermatogenesis by negatively regulating Adamts5. THERIOGENOLOGY. 2023 AugRead more>>
  • Mudassar Iqbal. et al. Baicalin inhibits apoptosis and enhances chondrocyte proliferation in thiram-induced tibial dyschondroplasia in chickens by regulating Bcl-2/Caspase-9 and Sox-9/Collagen-II expressions. ECOTOX ENVIRON SAFE. 2023 Dec;268:115689Read more>>
  • Lei Han. et al. Platelet-rich plasma-derived exosomes promote rotator cuff tendon-bone healing. INJURY. 2024 Feb;55:111212Read more>>
  • Qiu Yan. et al. Heme oxygenase 1 (HO1) regulates autophagy and apoptosis via the PI3K/AKT/mtor signaling pathway of yak sertoli cells. THERIOGENOLOGY. 2024 MaRead more>>
  • Yu Han. et al. High-precision bioactive scaffold with dECM and extracellular vesicles targeting 4E-BP inhibition for cartilage injury repair. MATER TODAY BIO. 2024 Aug;27:101114Read more>>
VALIDATION IMAGES