bs-41322P
[Protein]
Recombinant human CH25H protein, N-His
DATASHEET
Swiss Prot: O95992
Source: Recombinant human CH25H protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 140-272/272.
Storage Buffer: 0.01M TBS(pH7.4)
Storage: The product should be stored at -70°C or -20°C.
Background:
CH25H (Cholesterol 25-hydroxylase), also known as h25OH, is a 272 amino acid endoplasmic membrane protein that belongs to the sterol desaturase family. CH25H contains clusters of histidine residues essential for catalytic activity and is involved in cholesterol and lipid metabolism. CH25H catalyzes the formation of 25-hydroxycholesterol from cholesterol leading to the repression of cholesterol biosynthetic enzymes. CH25H regulates lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. CH25H utilizes diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.
Size: 100ug,500ug
Applications: ELISA()
Mol. Wt.: 14
Species: Others
For research use only. Not intended for diagnostic or therapeutic use.