bs-41250P
[Protein]
Recombinant human NLRP3 protein, C-His
DATASHEET
Entrez Gene: 114548
Swiss Prot: Q96P20
Source: Recombinant human NLRP3 protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 4-223/1036.
Storage Buffer: 0.01M TBS(pH7.4)
Storage: The product should be stored at -70°C or -20°C.
Background:
May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.
Size: 50ug,500ug
Applications: ELISA()
Mol. Wt.: 25.8
Species: Others
For research use only. Not intended for diagnostic or therapeutic use.