bs-41229P
[Protein]
Recombinant Human Pepsinogen C / PGC protein, C-His
DATASHEET
Entrez Gene: 5225
Swiss Prot: P20142
Source: Recombinant Human Pepsinogen C / PGC protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 16-388/388.
Storage Buffer: 0.01M TBS(pH7.4)
Storage: The product should be stored at -70°C or -20°C.
Background:
This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq].
Size: 100ug,500ug
Applications: ELISA()
Mol. Wt.: 40
Species: Others
For research use only. Not intended for diagnostic or therapeutic use.