bs-41175P
[Protein]
Recombinant human Cystatin-C protein, N-His
DATASHEET
Entrez Gene: 1471
Swiss Prot: P01034
Source: Recombinant human Cystatin-C protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 27-146/146.
Storage Buffer: 0.01M TBS(pH7.4)
Storage: The product should be stored at -70°C or -20°C.
Background:
Cystatin C or cystatin 3 (formerly gamma trace, post-gamma-globulin, or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.
Size: 100ug,500ug
Applications: ELISA()
Mol. Wt.: 15
Species: Others
For research use only. Not intended for diagnostic or therapeutic use.