bs-41112P
[Protein]
Recombinant human Creatine Kinase B protein, N-His
DATASHEET
Entrez Gene: 1152
Swiss Prot: P12277
Source: Recombinant human Creatine Kinase B protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 1-381/381.
Storage Buffer: 0.01M TBS(pH7.4)
Storage: The product should be stored at -70°C or -20°C.
Background:
The protein encoded by this gene, CK-BB, consists of a homodimer of two identical brain-type CK-B subunits. BB-CK is a cytoplasmic enzyme involved in cellular energy homeostasis, with certain fractions of the enzyme being bound to cell membranes, ATPases, and a variety of ATP-requiring enzymes in the cell. There, CK-BB forms tightly coupled microcompartments for in situ regeneration of ATP that has been used up. The encoded protein reversibly catalyzes the transfer of "energy-rich" phosphate between ATP and creatine or between phospho-creatine (PCr) and ADP. Its functional entity is a homodimer (CK-BB) in brain and smooth muscle as well as in other tissues and cells such as neuronal cells, retina, kidney, bone, etc. In heart, a heterodimer (CK-MB) shahil consisting of one CK-B brain-type CK subunit and one CK-M muscle-type CK subunit is prominently expressed. The encoded CK-BB and CK-MB proteins are members of the ATP:guanido phosphotransferase protein family.
Size: 100ug,500ug
Applications: ELISA()
Mol. Wt.: 43
Species: Others
For research use only. Not intended for diagnostic or therapeutic use.