bs-41073P
[Protein]
Recombinant mouse IL-1b protein, C-His
DATASHEET
Entrez Gene: 16176
Swiss Prot: P10749
Source: Recombinant mouse IL-1b protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 117-269/269.
Storage Buffer: 0.01M TBS(pH7.4)
Storage: The product should be stored at -70°C or -20°C.
Background:
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].
Size: 100ug,500ug
Applications: ELISA()
Mol. Wt.: 17
Species: Others
For research use only. Not intended for diagnostic or therapeutic use.