DATASHEET
Host:
Rabbit
Target Protein:
GPX1
Immunogen Range:
51-150/201
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
14775
Swiss Prot:
P11352
Source:
KLH conjugated synthetic peptide derived from mouse Glutathione Peroxidase 1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
This gene product belongs to the family of glutathione peroxidase, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. [provided by RefSeq].
PRODUCT SPECIFIC PUBLICATIONS
- Miyamoto, Kazuyuki, et al. "PACAP38 Suppresses Cortical Damage in Mice with Traumatic Brain Injury by Enhancing Antioxidant Activity." Journal of Molecular Neuroscience (2014): 1-10.Read more>>
- Wang, Yandi, et al. "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." Toxicology and Applied Pharmacology (2016).Read more>>
- Zhao, Yong, et al. "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." Scientific Reports 6 (2016): 37884.Read more>>
- Yun, Yang, et al. "Sulfate Aerosols Promote Lung Cancer Metastasis by Epigenetically Regulating the Epithelial-to-Mesenchymal Transition (EMT)." Environmental Science & Technology (2017).Read more>>
- Zhang, Weidong, et al. "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." Chemosphere (2017).Read more>>
- Liu R et al. Effect of Dietary Methionine Deficiency Followed by a Re-Feeding Phase on the Hepatic Antioxidant Activities of LambsAnimals (Basel).2020 Dec 23;11(1):7.Read more>>
- Shanshan Wang. et al. Effects of Coated Cysteamine on Oxidative Stress and Inflammation in Weaned Pigs. Animals-Basel. 2021 Aug;11(8):2217Read more>>
- Kuankuan Xiong. et al. Low-Concentration T-2 Toxin Attenuates Pseudorabies Virus Replication in Porcine Kidney 15 Cells. Toxins. 2022 Feb;14(2):121Read more>>
- Changjiang Liu. et al. JNK and Jag1/Notch2 co-regulate CXCL16 to facilitate cypermethrin-induced kidney damage. ECOTOX ENVIRON SAFE. 2022 Jun;238:113582Read more>>
- Yanan Hao. et al. Alginate Oligosaccharides Repair Liver Injury by Improving Anti-Inflammatory Capacity in a Busulfan-Induced Mouse Model. INT J MOL SCI. 2023 Jan;24(4):3097Read more>>
- Xinyu Wang. et al. Berberine modulates gut microbiota to attenuate cerebral ferroptosis induced by ischemia-reperfusion in mice. EUR J PHARMACOL. 2023 May;:175782Read more>>
- Depeng Fang. et al. ROS-responsive nanocomposite scaffolds for sustained releasing puerarin to achieve chondroprotection in OA rats. MATER DESIGN. 2023 Aug;:112214Read more>>
- Ulloa Miriam. et al. Prolactin is an Endogenous Antioxidant Factor in Astrocytes That Limits Oxidative Stress-Induced Astrocytic Cell Death via the STAT3/NRF2 Signaling Pathway. NEUROCHEM RES. 2024 Jul;49(7):1879-1901Read more>>
- Li Mou. et al. GRP78/IRE1 and cGAS/STING pathway crosstalk through CHOP facilitates iodoacetic acid-mediated testosterone decline. J HAZARD MATER. 2024 Sep;476:135101Read more>>
VALIDATION IMAGES
Mouse spleen lysates probed with Rabbit Anti-GPX1 Polyclonal Antibody, Unconjugated (bs-3882R) at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody for 90 min at 37˚C.
Lane 1: Mouse Liver tissue lysates; Lane 2: Mouse Spleen tissue lysates; Lane 3: Mouse Kidney tissue lysates; Lane 4: Rat Liver tissue lysates; Lane 5: Rat Heart tissue lysates; Lane 6: Rat Spleen tissue lysates; Lane 7: Rat Kidney tissue lysates probed with GPX1 Polyclonal Antibody, Unconjugated (bs-3882R) at 1:500 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.