bs-3735R-Biotin

DATASHEET

Host: Rabbit

Target Protein: DNA PK/PRKDC Thr2609

Modification Site: Thr2609

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5591

Source: KLH conjugated synthetic phosphopeptide derived from human PRKDC around the phosphorylation site of Thr2609

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 454

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.