bs-3735R-BF350

DATASHEET

Host: Rabbit

Target Protein: DNA PK/PRKDC Thr2609

Modification Site: Thr2609

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5591

Source: KLH conjugated synthetic phosphopeptide derived from human PRKDC around the phosphorylation site of Thr2609

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

DNA PK is the key component of the non-homologous end-joining (NHEJ) pathway of DSB repair in mammalian cells. DNA PK consists of a heterodimeric DNA-binding subunit (Ku70/80) and an approximately 465 kDa catalytic subunit (DNA PKcs). DNA PKcs is a serine/threonine protein kinase whose activity is greatly stimulated by its recruitment to DNA breaks by the Ku heterodimer.

Conjugation: AbBy Fluor® 350

Excitation/ Emission: 346nm/442nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 454

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.