bs-3724R-Cy5 [Conjugated Primary Antibody]
mu Opioid Receptor (Ser375) Antibody, Cy5 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
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DATASHEET

Host: Rabbit

Target Protein: mu Opioid Receptor Ser375

Modification Site: Ser375

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 25601

Swiss Prot: P33535

Source: KLH conjugated synthetic phosphopeptide derived from rat mu Opioid Receptor around the phosphorylation site of Ser375

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes one of three opioid receptors. The mu opioid receptor is the principal target of endogenous opioid peptides and opioid analgesic agents such a s beta-endorphn and enkephalins. The NM_001008503.1:c.118A>G allele had been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence is conflicting. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)

Predicted Molecular Weight: 44


Cross Reactive Species: Mouse
Others

Predicted Cross Reactive Species: Human
Rat
Dog
Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Brewer, Kori L., et al. "Dopamine D3 receptor dysfunction prevents anti-nociceptive effects of morphine in the spinal cord." Frontiers in Neural Circuits 8 (2014): 62.Read more>>
  • Laureano, D. P., et al. "Intrauterine growth restriction modifies the hedonic response to sweet taste in newborn pups-role of the accumbal μ-opioid receptors." Neuroscience (2016).Read more>>
  • Sanna MD et al. μ Opioid Receptor-Triggered Notch-1 Activation Contributes to Morphine Tolerance: Role of Neuron–Glia Communication. Mol Neurobiol. 2019 Jul 25. Read more>>
VALIDATION IMAGES