bs-3618R-FITC [Conjugated Primary Antibody]
HSD11B2 Polyclonal Antibody, FITC Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: HSD11B2

Immunogen Range: 151-250/405


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3291

Swiss Prot: P80365

Source: KLH conjugated synthetic peptide derived from human HSD11B2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 45


Cross Reactive Species: Human
Mouse
Rat
Horse

Predicted Cross Reactive Species: Dog

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Ding, Ying-xue, et al. "Regulation of glucocorticoid-related genes and receptors/regulatory enzyme expression in intrauterine growth restriction filial rats." Life Sciences (2016).Read more>>
  • Xu et al. Preeclampsia is associated with a deficiency of lipoxin A4, an endogenous anti-inflammatory mediator. (2014) Fertil.Steri. 102:282-290.e4Read more>>
  • Wang et al. Preeclampsia induced by cadmium in rats is related to abnormal local glucocorticoid synthesis in placenta. (2014) Reprod.Biol.Endocrino. 12:77Read more>>
  • Haojing Liuet al. Glucocorticoid Exposure Induces Preeclampsia via DampeningLipoxin A4, an Endogenous Anti-Inflammatory and Proresolving Mediator. Front Pharmacol. 2020 Jul 28;11:1131.Read more>>
  • Nakanishi Tomoya. et al. Cortisol induces follicle regression, while FSH prevents cortisol-induced follicle regression in pigs. Mol Hum Reprod. 2021 MayRead more>>
  • Xue-Ting Shi. et al. Gestational cadmium exposure impairs placental angiogenesis via activating GC/GR signaling. Ecotox Environ Safe. 2021 Nov;224:112632Read more>>
VALIDATION IMAGES