DATASHEET
Host:
Rabbit
Target Protein:
CD64/IGFR1
Immunogen Range:
101-200/374
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
2209
Swiss Prot:
P12314
Source:
KLH conjugated synthetic peptide derived from human CD64/IGFR1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
PRODUCT SPECIFIC PUBLICATIONS
- Venosa Alessandro. et al. Role of CCR2+ Myeloid Cells in Inflammation Responses Driven by Expression of a Surfactant Protein-C Mutant in the Alveolar Epithelium. Front Immunol. 2021 Apr;12:1348Read more>>
- Laura Lopez-Sanz. et al. Fc receptor activation mediates vascular inflammation and abdominal aortic aneurysm development. Clin Transl Med. 2021 Jul;11(7):e463Read more>>
- Yin Zhuang. et al. Exosomes Secreted by Nucleus Pulposus Stem Cells Derived From Degenerative Intervertebral Disc Exacerbate Annulus Fibrosus Cell Degradation via Let-7b-5p. Front Mol Biosci. 2021; 8: 766115Read more>>
VALIDATION IMAGES
Lane 1: rat lung lysates Lane 2: human colon carcinoma lysates probed with Anti CD64/IGFR1/FCGR1A Polyclonal Antibody, Unconjugated (bs-1251R) at 1:200 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in RT. Predicted band 41kD. Observed band size: 41kD.
Lane 1: U937 cell lysates probed with FCGR1A/CD64 Polyclonal Antibody, Unconjugated (bs-3511R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: Mouse Spleen tissue lysates; Lane 2: Mouse Lung tissue lysates; Lane 3: Mouse Liver tissue lysates; Lane 4: Mouse Kidney tissue lysates ; Lane 5: Mouse Raw264.7 cell lysates ; Lane 6: Rat Spleen tissue lysates; Lane 7: Rat Liver tissue lysates; Lane 8: Rat Kidney tissue lysates; Lane 9: Human THP-1 cell lysates; Lane 10: Human HL60 cell lysates probed with FCGR1A/CD64 Polyclonal Antibody, Unconjugated (bs-3511R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.