Host: Rabbit
Target Protein: ATOX1
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 475
Swiss Prot: O00244
Source: KLH conjugated synthetic peptide derived from human ATOX1
Purification: Purified by Protein A.
Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome. [provided by RefSeq, Jul 2008]
Size: 100ul
Concentration: 1ug/ul
Predicted Molecular Weight: 7
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.
Western blot analysis of extracts from normal (control) and ATOX1 knockout (KO) 293T cells, using ATOX1 antibody (bs-34235R) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.