bs-3405R-Biotin

DATASHEET

Host: Rabbit

Target Protein: PTPN11 Tyr584

Specificity: This phosphorylation site is homologous across the listed cross reactive species.

Modification Site: Tyr584

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5781

Swiss Prot: Q06124

Source: KLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr584

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 66

Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Horse
Chicken

For research use only. Not intended for diagnostic or therapeutic use.