bs-3019R-Cy5 [Conjugated Primary Antibody]
eIF4EBP1 (Thr37 + Thr46) Antibody, Cy5 Conjugated
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Host: Rabbit

Target Protein: e4EBP1 Thr37 + Thr46

Modification Site: Thr37 + Thr46

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1978

Swiss Prot: Q13541

Source: KLH conjugated synthetic phosphopeptide derived from human 4EBP1 around the phosphorylation site of Thr37/46

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 13


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Jasna Fri??i?. et al. The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts. Immunity. 2021 MaRead more>>
  • Xusheng Du. et al. RIOK3-mediated Akt phosphorylation facilitates synergistic replication of Mareks disease and reticuloendotheliosis viruses. VIRULENCE. 2022 Jul 06Read more>>
VALIDATION IMAGES