DATASHEET
Host:
Rabbit
Target Protein:
C3a Receptor
Immunogen Range:
401-482/482
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
719
Swiss Prot:
Q16581
Source:
KLH conjugated synthetic peptide derived from human C3a Receptor/C3aR
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
PRODUCT SPECIFIC PUBLICATIONS
- Shinjyo, Noriko, et al. "Complement Peptide C3a Promotes Astrocyte Survival in Response to Ischemic Stress." Molecular Neurobiology (2015): 1-12.Read more>>
- Ina Lackner. et al. Systemic and local cardiac inflammation after experimental long bone fracture, traumatic brain injury and combined trauma in mice. J Orthop Transl. 2021 May;28:39Read more>>
- Tushar A. Shah. et al. Therapeutic Hypothermia Inhibits the Classical Complement Pathway in a Rat Model of Neonatal Hypoxic-Ischemic Encephalopathy. Front Neurosci-Switz. 2021; 15: 616734Read more>>
- Ina Lackner. et al. Reaming of femoral fractures with different reaming irrigator aspirator systems shows distinct effects on cardiac function after experimental polytrauma. J Orthop Res. 2020 Dec;38(12):2608-2618Read more>>
- Liu, Tao. et al. Microarray-based analysis of renal complement components reveals a therapeutic target for lupus nephritis. Arthritis Res Ther. 2021 Dec;23(1):1-15Read more>>
- Choi, Yun Ju. et al. Promotion of the inflammatory response in mid colon of complement component 3 knockout mice. Sci Rep-Uk. 2022 Feb;12(1):1-17Read more>>
- Gong, Biao. et al. Complement C3a activates astrocytes to promote medulloblastoma progression through TNF-_. J NEUROINFLAMM. 2022 Dec;19(1):1-17Read more>>
- Lackner Ina. et al. Cardiac alterations following experimental hip fracture - inflammaging as independent risk factor. FRONT IMMUNOL. 2022 Sep;0:4835Read more>>
- Li Xiaoyu. et al. Mingjing granule inhibits the subretinal fibrovascular membrane of two-stage laser-induced neovascular age-related macular degeneration in rats. FRONT PHARMACOL. 2024 Jun;15Read more>>
- Jing Lu. et al. Exploring the Role of Neutrophil-Related Genes in Osteosarcoma via an Integrative Analysis of Single-Cell and Bulk Transcriptome. BIOMEDICINES. 2024 Jul;12(7):1513Read more>>
VALIDATION IMAGES
293T lysates probed with C3a Receptor Polyclonal Antibody, Unconjugated (bs-2955R) at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C.
A549 lysates probed with C3a Receptor Polyclonal Antibody, Unconjugated (bs-2955R) at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C.
Lane 1: Rat Spleen tissue lysates; Lane 2: Human A549 cell lysates; Lane 3: Human HL60 cell lysates; Lane 4: Human THP-1 cell lysates probed with C3a Receptor Polyclonal Antibody, Unconjugated (bs-2955R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.