DATASHEET
Host:
Rabbit
Target Protein:
ITGA6
Specificity:
Will recognize Isoform Alpha-6X1A
Immunogen Range:
1031-1130/1130
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
3655
Swiss Prot:
P23229
Source:
KLH conjugated synthetic peptide derived from human ITGA6
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome.
PRODUCT SPECIFIC PUBLICATIONS
- Niu, Zhiwei, et al. "Ras/ERK1/2 pathway regulates the self-renewal of dairy goat spermatogonia stem cells." Reproduction 149.5 (2015): 445-452.Read more>>
- Zheng, Liming, et al. "CD49f promotes proliferation of male dairy goat germline stem cells." Cell Proliferation (2016).Read more>>
- Torkamani, N., et al. "Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle." Stem Cells International 2016 (2016).Read more>>
- LEI, Qi-jing, et al. "Establishment and characterization of immortalized bovine male germline stem cell line." Journal of Integrative Agriculture (2017).Read more>>
- Wang L et al. Zoledronic acid inhibits the growth of cancer stem cell derived from cervical cancer cell by attenuating their stemness phenotype and inducing apoptosis and cell cycle arrest through the Erk1/6 and Akt pathways. J Exp Clin Cancer Res. 2019 Feb 21;38(1):93.Read more>>
- ae, Eunnyung. et al. Integrin _3_1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis. NAT COMMUN. 2022 Jul;13(1):1-15Read more>>
VALIDATION IMAGES
Lane 1: SW480 cell lysates; Lane 2: A549 cell lysates; Lane 3: Huvec cell lysates; Lane 4: A431 cell lysates probed with Integrin alpha 6 Polyclonal Antibody, Unconjugated (bs-2641R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: Human SW480 cell lysates; Lane 2: Human A549 cell lysates; Lane 3: Human HUVEC cell lysates; Lane 4: Human A431 cell lysates probed with Integrin alpha 6 Polyclonal Antibody, Unconjugated (bs-2641R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.