bs-2639R-Biotin [Conjugated Primary Antibody]
PGES2 Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: PGES2

Immunogen Range: 281-384/384


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 96979

Swiss Prot: Q8BWM0

Source: KLH conjugated synthetic peptide derived from mouse PGES2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (By similarity). May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 43


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Pig
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Chia, Yuan-Yi, et al. "The Antinociceptive Effect of Light-Emitting Diode Irradiation on Incised Wounds Is Correlated with Changes in Cyclooxygenase 2 Activity, Prostaglandin E2, and Proinflammatory Cytokines." Pain Research and Management 2017 (2017).Read more>>
  • Sutrisno, Sutrisno, et al. "The effect of genistein on TGF-β signal, dysregulation of apoptosis, cyclooxygenase-2 pathway, and NF-kB pathway in mice peritoneum of endometriosis model." Middle East Fertility Society Journal (2017).Read more>>
  • Liu, Yun, et al. "Activated hepatic stellate cells directly induce pathogenic Th17 cells in chronic hepatitis B virus infection." Experimental Cell Research(2017).Read more>>
  • MiKyung Song. et al. Saururus chinensis-controlled allergic pulmonary disease through NF-B/COX-2 and PGE2 pathways. 2020 Sep 24Read more>>
  • Amy Tran-Guzman. et al. In vitro impact of genistein and mono(2-ethylhexyl) phthalate (MEHP) on the eicosanoid pathway in spermatogonial stem cells. Reprod Toxicol. 2022 Jan;107:15Read more>>
  • Yu Liu. et al. Inhibition of Prostaglandin E2 Receptor EP3 Attenuates Oxidative Stress and Neuronal Apoptosis Partially by Modulating p38MAPK/FOXO3/Mul1/Mfn2 Pathway after Subarachnoid Hemorrhage in Rats. OXID MED CELL LONGEV. 2022 Dec 09;2022:7727616Read more>>
  • Nakatani Ayaka. et al. High-frequency near-infrared semiconductor laser irradiation suppressed experimental tooth movement-induced inflammatory pain markers in the periodontal ligament tissues of rats. LASER MED SCI. 2023 Dec;38(1):1-11Read more>>
  • Dong Keon Oh. et al. Bifidobacterium longum BORI inhibits pain behavior and chondrocyte death, and attenuates osteoarthritis progression. PLOS ONE. 2023 Jun;18(6):e0286456Read more>>
  • Soon-Young Lee. et al. Ginseng Berry Juice (GBJ) Regulates the Inflammation in Acute Ulcerative Mouse Models and the Major Bioactive Substances Are Ginsenosides Rb3, Rc, Rd, and Re. NUTRIENTS. 2024 Jan;16(7):1031Read more>>
  • Haojie Chen. et al. Association Between Vertebral Endplate Defects and Patient-reported Symptoms: An Immunohistochemical Study Investigating the COX-2/PGE-2/EP-4 Axis. SPINE J. 2024 ApRead more>>