bs-2531R [Primary Antibody]
NES/KLK10 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: NES1/KLK10

Immunogen Range: 65-165/276


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5655

Swiss Prot: O43240

Source: KLH conjugated synthetic peptide derived from human NES1/KLK10

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Has a tumor-suppressor role for NES1 in breast and prostate cancer.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 31


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Cow

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Li, Lei, et al. "Upregulated KLK10 inhibits esophageal cancer proliferation and enhances cisplatin sensitivity in vitro." Oncology Reports.Read more>>
  • Wang et al. Chemoprevention activity of dipyridamole in the MMTV-PyMT transgenic mouse model of breast cancer. (2013) Cancer.Prev.Res.(Phila. 6:437-47Read more>>
  • Shimura et al. Urinary kallikrein 10 predicts the incurability of gastric cancer. (2017) Oncotarge. 8:29247-29257Read more>>
  • Wei Cheng. et al. LRG1 promotes the apoptosis of pulmonary microvascular endothelial cells through KLK10 in chronic obstructive pulmonary disease. TOB INDUC DIS. 2024; 22: 10.18332/tid/186404Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded mouse hippocampus labeled with Anti- KLK10 Polyclonal Antibody, Unconjugated (bs-2531R) at 1:200 followed by conjugation to the secondary antibody


DU145 cell lysates probed with NES/Kallikrein 10 Polyclonal Antibody, Unconjugated (bs-2531R) at 1:500 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C.


MCF-7 cell lysates probed with NES/Kallikrein 10 Polyclonal Antibody, Unconjugated (bs-2531R) at 1:500 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.