DATASHEET
Host:
Rabbit
Target Protein:
CD151
Immunogen Range:
101-200/253
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
977
Swiss Prot:
P48509
Source:
KLH conjugated synthetic peptide derived from human CD151
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008].
PRODUCT SPECIFIC PUBLICATIONS
- Ceshu Gao. et al. Downregulation of CD151 restricts VCAM-1 mediated leukocyte infiltration to reduce neurobiological injuries after experimental stroke. J Neuroinflamm. 2021 Dec;18(1):1-16Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human colon cancer labeled with Anti-CD151/MER2/PETA-3 Polyclonal Antibody, Unconjugated (bs-2524R) at 1:200 followed by conjugation to the secondary antibody
Mouse heart lysates probed with Rabbit Anti-CD151 Polyclonal Antibody, Unconjugated (bs-2524R) at 1:300 overnight at 4˚C. Followed by a conjugated secondary antibody at 1:5000 for 90 min at 37˚C