bs-2518R-Cy5 [Conjugated Primary Antibody]
CD74 Polyclonal Antibody, Cy5 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD74

Immunogen Range: 151-250/296


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 972

Swiss Prot: P04233

Source: KLH conjugated synthetic peptide derived from human CD74

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)

Predicted Molecular Weight: 34


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Breda PC et al. Renal proximal tubular epithelial cells exert immunomodulatory function by driving inflammatory CD4+ T-cell responses. Am J Physiol Renal Physiol. 2019 Apr 24.Read more>>
  • Nan Du. et al. Adult astrocytes from reptiles are resistant to proinflammatory activation via sustaining Vav1 expression. J Biol Chem. 2021 Mar;:100527Read more>>
  • Aaron K. Chow. et al. Enteric Glia Regulate Lymphocyte Activation via Autophagy-Mediated MHC-II Expression. Cell Mol Gastroenter. 2021 JuRead more>>
  • Huiyuan Ji. et al. D-dopachrome tautomerase activates COX2/PGE2 pathway of astrocytes to mediate inflammation following spinal cord injury. J Neuroinflamm. 2021 Dec;18(1):1-16Read more>>
  • Siyu Li. et al. Effect of inorganic mercury exposure on reproductive system of male mice: Immunosuppression and fibrosis in testis. 2021 Sep 27Read more>>
  • Muhammad Ilyas Y.. et al. Effect of Immunomodulating Extract and Some Isolates from Etlingera rubroloba A.D. Poulsen Fruits on Diabetic Patients with Tuberculosis. MOLECULES. 2023 Jan;28(5):2401Read more>>
  • Jiawei Li. et al. Therapeutic targets of formononetin for treating prostate cancer at the single-cell level. AGING-US. 2024 Jun 30; 16(12): 1038010401Read more>>
  • Haofei Wang. et al. Proteomics analysis of deep fascia in acute compartment syndrome. PLOS ONE. 2024 Jul;19(7):e0305275Read more>>
VALIDATION IMAGES