bs-2428R [Primary Antibody]
IL-9 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: IL-9

Immunogen Range: 21-120/144


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 16198

Swiss Prot: P15247

Source: KLH conjugated synthetic peptide derived from mouse IL-9

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

The protein encoded by this gene is a cytokine that actsas a regulator of a variety of hematopoietic cells. This cytokinestimulates cell proliferation and prevents apoptosis. It functionsthrough the interleukin 9 receptor (IL9R), which activatesdifferent signal transducer and activator (STAT) proteins and thusconnects this cytokine to various biological processes. The geneencoding this cytokine has been identified as a candidate gene forasthma. Genetic studies on a mouse model of asthma demonstratedthat this cytokine is a determining factor in the pathogenesis ofbronchial hyperresponsiveness. [provided by RefSeq, Jul 2008].

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 16


Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Yao, Xiuhua, et al. "Neutralization of IL‐9 ameliorates symptoms of experimental autoimmune myasthenia gravis in rats by decreasing effector T cells and altering humoral responses." Immunology (2014).Read more>>
  • Lin, Yinyao, et al. "Expression of interleukin-9 and its upstream stimulating factors in rats with ischemic stroke." Neurological Sciences (2015): 1-8.Read more>>
  • Yang et al. Interleukin-9 Is Associated with Elevated Anti-Double-Stranded DNA Antibodies in Lupus-Prone Mice. (2015) Mol.Me. 21:364-70Read more>>
  • Yun Sun. et al. Inhibitory effects of catalpol on DNCB-induced atopic dermatitis and IgE-mediated mast cells reaction. INT IMMUNOPHARMACOL. 2024 Jan;126:111274Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded mouse lung labeled with Anti-IL-9 Polyclonal Antibody, Unconjugated (bs-2428R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Mouse lung lysates probed with IL-9 Polyclonal Antibody, Unconjugated (bs-2428R) at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C.