Host: Rabbit
Target Protein: Aβ1-42 (CT)
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 351
Swiss Prot: P05067
Source: KLH conjugated synthetic peptide derived from human Aβ1-42 (CT)
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid antibodies and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
Conjugation: RBITC
Excitation/ Emission: 540nm/625nm
Size: 100ul
Concentration: 1mg/ml
Applications:
IF(IHC-P)(1:100-500)
IF(IHC-F)(1:100-500)
IF(ICC)(1:100-500)
Predicted Molecular Weight: 87
Cross Reactive Species: Human
For research use only. Not intended for diagnostic or therapeutic use.