bs-2229R [Primary Antibody]
Brucella Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Brucella

Clonality: Polyclonal

Isotype: IgG

Source: whole cell protein of Brucella

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Brucellosis is a zoonotic infection caused by the bacterial genus Brucella. The bacteria are transmitted from animals to humans by ingestion through infected food products, direct contact with an infected animal, or inhalation of aerosols. The disease is an old one that has been known by various names, including Mediterranean fever, Malta fever, gastric remittent fever, and undulant fever. Humans are accidental hosts, but brucellosis continues to be a major public health concern worldwide and is the most common zoonotic infection.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Cross Reactive Species: Mouse
Bacteria
(Brucella)

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wareth, Gamal, et al. "Experimental infection of chicken embryos with recently described Brucella microti: Pathogenicity and pathological findings."Comparative Immunology, Microbiology and Infectious Diseases (2015).Read more>>
  • Khalaf OH et al. The NOD-scid IL2rγnull Mouse Model Is Suitable for the Study of Osteoarticular Brucellosis and Vaccine Safety. Infect Immun. 2019 May 21;87(6). pii: e00901-18. Read more>>
  • Stranahan LW et al. Characterization of Brucella canis infection in mice. PLoS One. 2019 Jun 20;14(6):e0218809. Read more>>
  • Hensel ME et al. Vaccine Candidate Brucella melitensis 16MvjbR Is Safe in a Pregnant Sheep Model and Confers Protection. mSphere. 2020 May 13;5(3):e00120-20.Read more>>
  • Raquel M et al. Evaluation of the safety profile of the vaccine candidate Brucella melitensis 16MvjbR strain in GoatsVaccine.2021 Jan 15;39(3):617-625.Read more>>
  • Xin Hu. et al. The role of CXCR3 and its ligands expression in Brucellar spondylitis. Bmc Immunol. 2020 Dec;21(1):1-8Read more>>
  • Martha E. Hensel. et al. Intratracheal Inoculation with Brucella melitensis in the Pregnant Guinea Pig Is an Improved Model for Reproductive Pathogenesis and Vaccine Studies. Infect Immun. 2020 Sep;88(10):e00204-2Read more>>
  • Fengguang Guo. et al. Live attenuated bacterium limits cancer resistance to CAR-T therapy by remodeling the tumor microenvironment. J Immunother Cancer. 2022 Jan;10(1):e00376Read more>>
  • Kelsey Michelle Wells. et al. Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense. ELIFE. 2022; 11: e73625Read more>>
  • Stranahan Lauren W.. et al. Primary and memory immune responses against rough Brucella canis are less robust compared to smooth B. abortus and B. melitensis following intratracheal infection in mice. FRONT IMMUNOL. 2022 Aug;0:4494Read more>>
  • Martha E. Hensel. et al. Intratracheal inoculation results in Brucella-associated reproductive disease in male mouse and guinea pig models of infection.. FRONT MICROBIOL. 2022 Oct;13:1029199-1029199Read more>>
  • Charles R. Moley. et al. Innate Lymphoid Cells and Interferons Limit Neurologic and Articular Complications of Brucellosis. AM J PATHOL. 2023 MayRead more>>
  • Agustn Rebollada-Merino. et al. Immunopathology of early and advanced epididymis lesions caused by Brucella ovis in rams. VET IMMUNOL IMMUNOP. 2023 Jul;261:110621Read more>>
  • Heling Xu. et al. A genome-wide CRISPR screen identified host genes essential for intracellular Brucella survival. MICROBIOL SPECTR. 2024 Feb 2Read more>>