bs-21452R [Primary Antibody]
ADRB2 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: ADRB2

Immunogen Range: 301-400/413


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 154

Swiss Prot: P07550

Source: KLH conjugated synthetic peptide derived from human ADRB2

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF()
ICC(1:100-500)

Predicted Molecular Weight: 46


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Sheep
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Gloria Lazzeri. et al. Norepinephrine Protects against Methamphetamine Toxicity through 2-Adrenergic Receptors Promoting LC3 Compartmentalization. Int J Mol Sci. 2021 Jan;22(13):7232Read more>>
  • Yanjie Lu. et al. Chronic stress promotes gastric cancer progression via the adrenoceptor beta 2/PlexinA1 pathway. CELL STRESS CHAPERON. 2024 Feb;29:201Read more>>
VALIDATION IMAGES

Lane 1: Mouse Heart tissue lysates; Lane 2: Mouse Stomach tissue lysates; Lane 3: Rat Heart tissue lysates; Lane 4: Human A431 cell lysates probed with ADRB2 Polyclonal Antibody, Unconjugated (bs-21452R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.