bs-2127R-APC [Conjugated Primary Antibody]
5HT4 Receptor Polyclonal Antibody, APC Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: 5HT4 Receptor

Immunogen Range: 21-120/388


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3360

Swiss Prot: Q13639

Source: KLH conjugated synthetic peptide derived from human 5-HTR4

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 43


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Cow
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Siyuan Peng. et al. LMWP (S3-3) from the Larvae of Musca domestica Alleviate D-IBS by Adjusting the Gut Microbiota. MOLECULES. 2022 Jan;27(14):4517Read more>>
  • Eri Kitayama. et al. Functional Expression of IP, 5-HT4, D1, A2A, and VIP Receptors in Human Odontoblast Cell Line. BIOMOLECULES. 2023 Jun;13(6):879Read more>>
  • Yuki Kunioku. et al. Intracellular cAMP Signaling Pathway via Gs Protein-Coupled Receptor Activation in Rat Primary Cultured Trigeminal Ganglion Cells. BIOMEDICINES. 2023 Sep;11(9):2347Read more>>
  • Liu Qihong. et al. Effects of Liqi Tongbian decoction on gut microbiota, SCFAs production, and 5-HT pathway in STC rats with Qi Stagnation Pattern. FRONT MICROBIOL. 2024 Mar;15Read more>>
VALIDATION IMAGES