DATASHEET
Host:
Rabbit
Target Protein:
Angiotensin 2 Type 1 Receptor
Immunogen Range:
201-300/359
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
185
Swiss Prot:
P30556
Source:
KLH conjugated synthetic peptide derived from human AT1R
Purification:
Purified by Protein A.
Storage Buffer:
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].
Conjugation:
PE
Excitation/ Emission:
496,564nm/578nm
Size:
100ul
Concentration:
1ug/ul
Applications:
FCM(1:20-100)
39
Human
Predicted Cross Reactive Species:
Mouse
Rat
Cow
Rabbit
For research use only. Not intended for diagnostic or therapeutic use.