bs-20788R-APC

DATASHEET

Host: Rabbit

Target Protein: CCR4

Immunogen Range: 171-220/360

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1233

Swiss Prot: P51679

Source: KLH conjugated synthetic peptide derived from human CCR4

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 40

Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.