bs-20689R-FITC [Conjugated Primary Antibody]
Integrin alpha X /CD11c Polyclonal Antibody, FITC Conjugated
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Host: Rabbit

Target Protein: Integrin alpha X /CD11c

Immunogen Range: 301-400/1163


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3687

Swiss Prot: P20702

Source: KLH conjugated synthetic peptide derived from human Integrin alpha X /CD11c

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq].

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)

Predicted Molecular Weight: 126 kDa


Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

The Jurkat(H) cells were incubated in 5%BSA to block non-specific protein-protein interactions (30 min at r.t.). Primary Antibody (green): FITC conjugated Rabbit Anti-CD11c antibody (bs-20689R-FITC): 2 μg/10^6 cells; Isotype Control (orange): Rabbit-FITC IgG (bs-60295P-FITC). Blank control (black): PBS. Acquisition of 20,000 events was performed.