DATASHEET
Host:
Rabbit
Target Protein:
N-cadherin
Immunogen Range:
701-800/906
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
1000
Swiss Prot:
P19022
Source:
KLH conjugated synthetic peptide derived from human N-cadherin
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
PRODUCT SPECIFIC PUBLICATIONS
- Qinhong Xu. et al. Overexpression of circ_0001445 decelerates hepatocellular carcinoma progression by regulating miR-942-5p/ALX4 axis. Biotechnol Lett. 2020 Dec;42(12):2735-2747Read more>>
- Yue Deng. et al. ARID5B promoted the histone demethylation of SORBS2 and hampered the metastasis of ovarian cancer. PATHOL RES PRACT. 2023 Dec;252:154911Read more>>
VALIDATION IMAGES
Mouse Cerebrum lysates probed with N-cadherin Polyclonal Antibody, Unconjugated (bs-20622R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: Mouse Testis lysates; Lane 2: Mouse Cerebrum lysates; Lane 3: Rat Testis lysates; Lane 4: Rat Cerebellum lysates; Lane 5: Human Panc-1 cell lysates; Lane 6: Human A549 cell lysates; Lane 7: Human SH-SY5Y cell lysates; Lane 8: Human U251 cell lysates probed with N-cadherin Polyclonal Antibody, Unconjugated (bs-20622R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.