DATASHEET
Host:
Rabbit
Target Protein:
AQP9
Immunogen Range:
201-295/295
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
366
Swiss Prot:
O43315
Source:
KLH conjugated synthetic peptide derived from human AQP9
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol.
PRODUCT SPECIFIC PUBLICATIONS
- Chau, David, et al. "Azacytidine sensitizes acute myeloid leukemia cells to arsenic trioxide by up-regulating the arsenic transporter aquaglyceroporin 9."Journal of Hematology & Oncology 8.1 (2015): 46.Read more>>
- DAVID, CHAU HAU WING. "POTENTIAL THERAPEUTIC APPLICATION OF ARSENIC TRIOXIDE IN ACUTE MYELOID LEUKAEMIA."Read more>>
- DAVID, CHAU HAU WING. "POTENTIAL THERAPEUTIC APPLICATION OF ARSENIC TRIOXIDE IN ACUTE MYELOID LEUKAEMIA."Read more>>
- Vicente‐Carrillo, A., et al. "Membrane Stress During Thawing Elicits Redistribution of Aquaporin 7 But Not of Aquaporin 9 in Boar Spermatozoa."Reproduction in Domestic Animals (2016).Read more>>
- Sato K et al. Different Prognostic Implications of Aquaporin-1 and Aquaporin-5 Expression among Different Histological Types of Ovarian Carcinoma.Pathol Oncol Res. 2018 Jul 19. Read more>>
- Ji Woo Im. et al. Stichoposide C and Rhizochalin as Potential Aquaglyceroporin Modulators. MAR DRUGS. 2024 Aug;22(8):335Read more>>
VALIDATION IMAGES
Lane 1: Mouse intestine lysates probed with Rabbit Anti-AQP9 Polyclonal Antibody, Unconjugated (bs-2060R) at 1:300 overnight at 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:5000 for 90 min at RT.
Mouse liver lysates probed with Rabbit Anti-AQP9 Polyclonal Antibody, Unconjugated (bs-2060R) at 1:300 overnight at 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 for 90 min at RT.
Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti-AQP9 Polyclonal Antibody, Unconjugated (bs-2060R) at 1:200 followed by conjugation to the secondary antibody and DAB staining\n
A549 probed with AQP9 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated (bs-2060R-A647) at 1:100 for 30 minutes compared to control cells (blue) and isotype control (orange).