DATASHEET
Host:
Rabbit
Target Protein:
TGF beta 1
Immunogen Range:
331-390/390
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
7040
Swiss Prot:
P01137
Source:
KLH conjugated synthetic peptide derived from human TGF beta 1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background:
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
PRODUCT SPECIFIC PUBLICATIONS
- Ye Tian. et al. The Mitigatory Effect of Shen-Qi Compound on the Diabetic Thoracic Aortic Complications through Inhibiting the Inflammatory Microenvironment by miR-223-3p/RBP-J/IRF8 Axis. EVID-BASED COMPL ALT. 2022 Sep 28;2022:6686931Read more>>
- Tuli Kou. et al. Effects of berberine hydrochloride on left ventricular structure and function in rats with myocardial hypertrophy. ACTA CARDIOL. 2023 Feb 28Read more>>
- Xiao-ping Shui. et al. Effects of millimeter-wave for preventing joint stiffness in the immobilized knee rat model. KNEE. 2023 Jun;42:236Read more>>
- Zemei Liu. et al. Pharmacodynamic study: Astragaloside IV/chitosan/polylactic acid composite electrospinning scaffold for wound healing in diabetic rats. J DRUG DELIV SCI TEC. 2024 Apr;:105632Read more>>
- Xiangyan Xie. et al. Injectable, stable, and biodegradable hydrogel with platelet-rich plasma induced by l-serine and sodium alginate for effective treatment of intrauterine adhesions. INT J BIOL MACROMOL. 2024 Jun;270:132363Read more>>
- Chong-Xiao Yun. et al. Construction of the pulmonary bio-adhesive delivery system of nintedanib nanocrystalline for effective treatment of pulmonary fibrosis. INT J PHARMACEUT. 2024 Jul;660:124302Read more>>
- Hongyi Lv. et al. Injectable, degradable, and mechanically adaptive hydrogel induced by L-serine and allyl-functionalized chitosan with platelet-rich plasma for treating intrauterine adhesions. ACTA BIOMATER. 2024 JulRead more>>
VALIDATION IMAGES
Lane 1:Human A549 cell lysates; Lane 2: Mouse Stomach lysates probed with TGF beta Polyclonal Antibody, Unconjugated (bs-20411R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: Mouse Stomach tissue lysates; Lane 2: Mouse Liver tissue lysates; Lane 3: Mouse Placenta tissue Lysates; Lane 4: Mouse NIH/3T3 cell Lysates; Lane 5: Rat Liver tissue Lysates probed with TGF beta 1 Polyclonal Antibody, Unconjugated (bs-20411R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.