DATASHEET
Host:
Rabbit
Target Protein:
SLC8A2
Immunogen Range:
601-700/921
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
6543
Swiss Prot:
Q9UPR5
Source:
KLH conjugated synthetic peptide derived from human SLC8A2
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity).
PRODUCT SPECIFIC PUBLICATIONS
- Zhang J et al. TRPV4 Complexes With the Na/Ca 2 Exchanger and IP 3 Receptor 1 to Regulate Local Intracellular Calcium and Tracheal Tension in Mice. Front. Physiol., 06 December 2019.Read more>>
- Zhixiu Xia. et al. NCX3 alleviates ethanol-induced apoptosis of SK-N-SH cells via the elimination of intracellular calcium ions. Toxicol In Vitro. 2021 Apr;72:105104Read more>>
- Zhixiu Xia. et al. The downregulation of NCXs is positively correlated with the prognosis of stage IICIV colon cancer. World J Surg Oncol. 2021 Dec;19(1):1-14Read more>>
- Yan Jie. et al. T-type voltage-gated channels, Na+/Ca2+-exchanger, and calpain-2 promote photoreceptor cell death in inherited retinal degeneration. CELL COMMUN SIGNAL. 2024 Dec;22(1):1-24Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded rat kidney labeled with Anti- NCX2/SLC8A2 Polyclonal Antibody, Unconjugated (bs-1997R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Formalin-fixed and paraffin embedded rat brain labeled with Anti- NCX2/SLC8A2 Polyclonal Antibody, Unconjugated (bs-1997R) at 1:200 followed by conjugation to the secondary antibody and DAB staining