bs-1955R-Biotin [Conjugated Primary Antibody]
CCL2 Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CCL2

Immunogen Range: 30-80/99


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 6347

Swiss Prot: P13500

Source: KLH conjugated synthetic peptide derived from human CCL2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. Augments monocyte anti-tumor activity. Has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Yang et al. CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway. (2016) Oncotarge. 7:15632-47Read more>>
  • Ma WJ et al. Biliary antibiotics irrigation for E. coli-induced chronic proliferative cholangitis and hepatolithiasis: A pathophysiological study in rabbits. Clin Res Hepatol Gastroenterol. 2019 Aug 13. pii: S2210-7401(19)30173-1.Read more>>
  • Hirokazu Konishi. et al. Effect of pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor modular (SPPARM), in atherosclerosis model using low density lipoprotein receptor knock-out swine with balloon injury. Plos One. 2020 Nov;15(11):e0241195Read more>>
  • Jin-Peng Chen. et al. Resolvin D2 prevents inflammation and oxidative stress in the retina of streptozocin-induced diabetic mice. Int J Clin Exp Patho. 2020; 13(8): 1986C1994Read more>>
  • Peng Liu. et al. Mechanism of transepithelial migration of lymphocytes into the milk in porcine mammary glands. J Reprod Immunol. 2021 Oct;:10344Read more>>
  • Li, Yuchen. et al. Porcine intraepithelial lymphocytes undergo migration and produce an antiviral response following intestinal virus infection. Commun Biol. 2022 Mar;5(1):1-16Read more>>
  • Dr. Xiaoli Wang. et al. HIV-1 Tat protein-mediated inflammatory response inhibits the erythroid hematopoietic support function of bone marrow mesenchymal stem cells. AIDS RES HUM RETROV. 2022 Aug 16Read more>>
  • Hirona Kugo. et al. Tricaprin can prevent the development of AAA by attenuating aortic degeneration. BIOMED PHARMACOTHER. 2023 Apr;160:114299Read more>>
  • Xiang Gao. et al. Effects of myeloperoxidase on inflammatory responses with hypoxia in Citrobacter rodentium-infectious mice. IMMUN INFLAMM DIS. 2024 Feb;12(2):e1157Read more>>
  • Hu Qiang. et al. A New Modulator of Neuroinflammation in Diabetic Retinopathy: USP25. INFLAMMATION. 2024 Mar;:1-16Read more>>
  • Linxu Wu. et al. Mechanistic role of RND3-regulated IL33/ST2 signaling on cardiomyocyte senescence. LIFE SCI. 2024 Jul;348:122701Read more>>
  • Xue Zhang. et al. Therapeutic potential of flavopiridol in diabetic retinopathy: Targeting DDX58. INT IMMUNOPHARMACOL. 2024 Aug;137:112504Read more>>
  • Haipiao Huang. et al. Jian-Pi-Yi-Shen formula ameliorates renal fibrosis-induced anemia in rats with chronic kidney disease. J ETHNOPHARMACOL. 2024 Dec;335:118607Read more>>