Host: Rabbit
Target Protein: CRLR/CGRPR1
Immunogen Range: 281-380/461
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 10203
Swiss Prot: Q16602
Source: KLH conjugated synthetic peptide derived from human CGRPR1
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
Conjugation: FITC
Excitation/ Emission: 494nm/518nm
Size: 100ul
Concentration: 1ug/ul
Applications:
WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(ICC)(1:50-200)
Predicted Molecular Weight: 50
Cross Reactive Species:
Human
Mouse
Predicted Cross Reactive Species: Rat
For research use only. Not intended for diagnostic or therapeutic use.
- Jablonski, Heidrun, et al. "Calcitonin Gene-Related Peptide Modulates the Production of Pro-Inflammatory Cytokines Associated with Periprosthetic Osteolysis by THP-1 Macrophage-Like Cells." Neuroimmunomodulation (2014).Read more>>
- Pauza AG et al. Alterations in enteric calcitonin gene-related peptide in patients with colonic diverticular disease. (2018) Autonomic Neuroscience.Sep 18. pii: S1566-0702(18)30176-0 Read more>>
- Muschter D et al. Sensory neuropeptides are required for bone and cartilage homeostasis in a murine destabilization-induced osteoarthritis model. Bone.?2020 Jan 8;133:115181.?Read more>>
- Hou K et al. Role of Calcitonin Gene-Related Peptide in Nociceptive Modulationin Anterior Cingulate Cortex of Na?ve Rats and Rats With Inflammatory Pain. Front Pharmacol. 2020 Jun 26;11:928.Read more>>
- Tanja Niedermair? et al. Absence of -calcitonin gene-related peptide modulates bone remodeling properties of murine osteoblasts and osteoclasts in an age-dependent way. Mech Ageing Dev. 2020 Jul;189:111265.Read more>>
- Lin-Lin Wang. et al. Role of calcitonin gene-related peptide in pain regulation in the parabrachial nucleus of naive rats and rats with neuropathic pain. Toxicol Appl Pharm. 2021 Mar;414:115428Read more>>
- Jessika Appelt. et al. The neuropeptide calcitonin gene-related peptide alpha is essential for bone healing. Ebiomedicine. 2020 Sep;59:10297Read more>>
- aranowsky, Anke. et al. Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment. Bone Res. 2022 Jan;10(1):1-15Read more>>
- E.R. Moore. et al. CGRP and Shh Mediate the Dental Pulp Cell Response to Neuron Stimulation:. J DENT RES. 0;()Read more>>
- Romina Mancinelli. et al. The Effects of Taurocholic Acid on Biliary Damage and Liver Fibrosis Are Mediated by Calcitonin-Gene-Related Peptide Signaling. CELLS-BASEL. 2022 Jan;11(9):1591Read more>>
- Ftima Gimeno-Ferrer. et al. From spreading depolarization to epilepsy with neuroinflammation: The role of CGRP in cortex. EXP NEUROL. 2022 Oct;356:114152Read more>>
- Jana, Barbara. et al. Involvement of the calcitonin gene-related peptide system in the modulation of inflamed uterus contractile function in pigs. SCI REP-UK. 2022 Nov;12(1):1-14Read more>>
- Shengcai Gu. et al. Interfering with CALCRL expression inhibits glioma proliferation, promotes apoptosis, and predicts prognosis in low-grade gliomas. ANN TRANSL MED. 2022 Dec;10(23):1277Read more>>
- Laixi Luo. et al. Calcitonin gene-related peptide and its receptor plays important role in nociceptive regulation in the arcuate nucleus of hypothalamus of rats with inflammatory pain. BEHAV BRAIN RES. 2023 Feb;:114351Read more>>
- Shusuke Iwata. et al. Adrenomedullin Enhances Mouse Gustatory Nerve Responses to Sugars via T1R-Independent Sweet Taste Pathway. NUTRIENTS. 2023 Jan;15(13):2941Read more>>
- Jiang Shan. et al. Transcript-dependent effects of the CALCA gene on the progression of post-traumatic osteoarthritis in mice. COMMUN BIOL. 2024 Feb;7(1):1-12Read more>>