bs-1719R-Cy5 [Conjugated Primary Antibody]
HPV16 E6 + HPV18 E6 Polyclonal Antibody, Cy5 Conjugated
www.biossusa.com
[email protected]
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DATASHEET

Host: Rabbit

Target Protein: HPV16 E6 + HPV18 E6

Specificity: This antibody may also detect HPV45 E6, HPV68 E6, HPV39 E6, and HPV35 E6

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1489078, 1489088

Swiss Prot: P03126, P06463

Source: KLH conjugated synthetic peptides from HPV16 E6 + HPV18 E6

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Human Papilloma virus (HPV) is responsible for the development of type and tissue specific papilloma in the oral cavity and in the larynx. In the skin papilloma virus can cause different types of warts and in the ano-genital region it is associated with condyloma or carcinoma. HPV types 16 and 18 seem to be responsible for the development of some carcinoma like cervical carcinoma.

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 11


Cross Reactive Species: Human
Virus
Others
(HPV16/HPV18)

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Yang JH et al. HPV16 E6/E7 upregulate hTERC mRNA and gene amplification levels by relieving the effect of LKB1 on Sp1 phosphorylation in lung cancer cells:. Ther Adv Med Oncol.2020 May 12;12:1758835920917562.Read more>>
  • Xiaona Chen. et al. CXCL10 Produced by HPV-Positive Cervical Cancer Cells Stimulates Exosomal PDL1 Expression by Fibroblasts via CXCR3 and JAK-STAT Pathways. Front Oncol. 2021; 11: 62935Read more>>