bs-1665R-Biotin [Conjugated Primary Antibody]
VEGF-A Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: VEGF-A

Immunogen Range: 81-132/232


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7422

Swiss Prot: P15692

Source: KLH conjugated synthetic peptide derived from human VEGF-A

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 24


Cross Reactive Species: Human
Mouse
Rat
Sheep

Predicted Cross Reactive Species: Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Li et al. Dual character of flavonoids in attenuating and aggravating ischemia-reperfusion-induced myocardial injury. (2017) Exp.Ther.Me. 14:1307-1314Read more>>
  • Gu et al. Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway. (2017) Oncotarget. 8:104104-104112Read more>>
  • Song et al. Effects of HSYA on the proliferation and apoptosis of MSCs exposed to hypoxic and serum deprivation conditions. (2018) Exp.Ther.Med. 15:5251-5260Read more>>
  • Chai D et al. β2-microglobulin has a different regulatory molecular mechanism between ER+ and ER- breast cancer with HER2.BMC Cancer. 2019 Mar 12;19(1):223.Read more>>
  • He Y et al. Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep. Animals (Basel). 2019 Sep 11;9(9). pii: E673. Read more>>
  • Tort S et al. The effect of a new wound dressing on wound healing: Biochemical and histopathological evaluation. Burns. 2019 Dec 17. pii: S0305-4179(18)30976-8.Read more>>
  • Lashkarinia SS et al. Spatiotemporal remodeling of embryonic aortic arch: stress distribution, microstructure, and vascular growth in silico. Biomech Model Mechanobiol. 2020 Mar 4. Read more>>
  • Li Y et al. Study on the Anticancer Effect of an Astragaloside- and Chlorogenic Acid-Containing Herbal Medicine (RLT-03) in Breast Cancer. Evid Based Complement Alternat Med. 2020 Jun 10;2020:1515081.Read more>>
  • Xinrong Wang. et al. Vascular morphology and expression of angiogenic factors in sheep ovaries and their relation with the lambing rate. Reprod Domest Anim. 2020 Sep;55(9):1132-1138Read more>>
  • Li Yanchu. et al. Effects of a Chlorogenic Acid-Containing Herbal Medicine (LASNB) on Colon Cancer. Evid-Based Compl Alt. 2021;2021:9923467Read more>>
  • Tardalkar, Kishor. et al. Heparin Immobilization of Tissue Engineered Xenogeneic Small Diameter Arterial Scaffold Improve Endothelialization. Tissue Eng Regen Med. 2022 Jan;:1-19Read more>>
  • Zhang Tianyao. et al. XSSJS inhibits hepatic fibrosis by promoting the mir29b-3p/VEGFA axis in vitro and in vivo. Bioscience Rep. 2022 Feb;():BSR20212241Read more>>
  • Rajendra K. Singh. et al. Diabetic bone regeneration with nanoceria-tailored scaffolds by recapitulating cellular microenvironment: Activating integrin/TGF- co-signaling of MSCs while relieving oxidative stress. BIOMATERIALS. 2022 Aug;:121732Read more>>
  • Min Long. et al. Changes in arterial blood vessels and VEGF and Ang-1 expression in pregnant and non-pregnant yak uterine caruncle. REPROD DOMEST ANIM. 2022 AugRead more>>
  • Tardalkar, Kishor R.. et al. Heparin coated decellularized xenogeneic small diameter vascular conduit for vascular repair with early luminal reendothelialization. CELL TISSUE BANK. 2022 Nov;:1-21Read more>>
  • Ge Ling Ying. et al. Management of experimental trabeculectomy filtering blebs via crosslinking of the scleral flap inhibited vascularization. GRAEF ARCH CLIN EXP. 2023 Nov;:1-11Read more>>
  • Feng Qiu. et al. The mechanism of Chebulae Fructus Immaturus promote diabetic wound healing based on network pharmacology and experimental verification. J ETHNOPHARMACOL. 2024 Mar;322:117579Read more>>
  • Ke Minhui. et al. Establishment and study of a rat internal haemorrhoid model. SCI REP-UK. 2023 Dec;13(1):1-1Read more>>
  • Demircan Volkan. et al. Evaluation of therapeutic use of a combination of pentoxifylline and vitamin E in radiation-induced renal fibrosis. SCI REP-UK. 2024 Mar;14(1):1-14Read more>>
  • Jingjunjiao Long. et al. Nanosilicate-reinforced GelMA-PEGDA hydrogel promotes angiogenesis for bone regeneration. INT J BIOL MACROMOL. 2024 Jun;:133202Read more>>
  • Elif Seda zdemir. et al. The effect of folic acid supplementation and folate deficiency on embryo implantation. REPROD BIOL. 2024 Sep;24:100895Read more>>
  • Chih-Ching Li. et al. Therapeutic Effect of Lecigel, CetiolCC, Activonol-6, Activonol-M, 1,3-Propanediol, Soline, and Fucocert (LCAA-PSF) Treatment on Imiquimod-Induced Psoriasis-like Skin in Mice. INT J MOL SCI. 2024 Jan;25(14):772Read more>>
  • Yuan Xu. et al. Glycine Receptor Beta Subunit (GlyR-) Promotes Potential Angiogenesis and Neurological Regeneration during Early-Stage Recovery after Cerebral Ischemia Stroke/Reperfusion in Mice. J INTEGR NEUROSCI. 2024 Aug;23(8):145Read more>>