bs-1586R-FITC [Conjugated Primary Antibody]
VEGF-C Polyclonal Antibody, FITC Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: VEGF-C

Immunogen Range: 321-415/415


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 22341

Swiss Prot: P97953

Source: KLH conjugated synthetic peptide derived from mouse VEGF-C

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 46


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhuo, Wei, et al. "The CXCL12?CCXCR4 Chemokine Pathway: A Novel Axis Regulates Lymphangiogenesis."Clinical Cancer Research 18.19 (2012): 5387-5398.lRead more>>
  • He, Ting, et al. "Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p." Cancer Letters (2015).Read more>>
  • Alunno, Alessia, et al. "Mobilization of lymphatic endothelial precursor cells and lymphatic neovascularization in primary Sjögrens syndrome." Journal of Cellular and Molecular Medicine (2016).Read more>>
  • Cialdai, Francesca, et al. "Modeled Microgravity Affects Fibroblast Functions Related to Wound Healing." Microgravity Science and Technology: 1-12.Read more>>
  • Shin et al. Expression of vascular endothelial growth factor-C (VEGF-C) and its receptor (VEGFR-3) in the glial reaction elicited by human mesenchymal stem cell engraftment in the normal rat brain. (2015) J.Histochem.Cytochem. 63:170-80Read more>>
  • Alunno et al. Mobilization of lymphatic endothelial precursor cells and lymphatic neovascularization in primary Sjögren's syndrome. (2016) J.Cell.Mol.Med. 20:613-22Read more>>
  • Ferrão JSP et al. Vascular endothelial growth factor C treatment for mouse hind limb lymphatic revascularization. Vet Med Sci. 2019 Feb 11. Read more>>
  • Li Li. et al. Circ_LPAR3 promotes the progression of oral squamous cell carcinoma (OSCC). Biochem Bioph Res Co. 2021 DecRead more>>
  • Michiko Jo. et al. Impact of Goreisan components on rat mesenteric collecting lymphatic vessel pumping. MICROCIRCULATION. 2022 Oct;:e12788Read more>>
VALIDATION IMAGES